If your provider offers this test, ask questions. What will it actually tell me? What is the next step? What are the risks and benefits? How will this help me have a healthier baby? And, ask yourself: Would I opt for the more extensive testing, even if it might add risk to the pregnancy? Would I choose to abort if the amnio indicates the baby is not perfect?
You don't have to have this screening unless you want it. Many women opt out based on these questions. We have seen women become very nervous following an abnormal screen; not able to relax and enjoy their pregnancies until they were certain all was well with the baby. In most cases, the baby is fine, but it can help you to determine some genetic defects in advance and with the additional testing may help the mother to deal with the circumstances better.
The important thing is to understand this is your decision to make. Click on the post title for some additional comments on this subject, including some reader responses regarding their own experiences. About.com also discusses prenatal testing here.
Read about one mother's experience with a false-positive screening here.